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Nootropics – Ranking Of Best To Worst (Modafinil, Phenylpiracetam, Ashwagandha)

March 29, 2019 / 16 Comments



I’ll rank nootropics during this video while taking into consideration my experience and research on these very powerful cognitive supplements.

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16 Comments

  • Joseph B

    April 3, 2019 at 12:22 am Reply

    I cannot say much about the chart because I have not tried that many nootropics before. I am going to be attempting a Selegiline regiment soon and I believe it will work for me wonderfully well. Selegiline has been shown to be very beneficial for many people who have tried it. I also have heard many reports of it not being such a pleasant experience. The difference has to do with the varying levels of dopamine levels that a person has when using Selegiline. If your dopamine is fine and well off already then selegiline would not be a good idea to administer in any amounts higher than a very low dose for life extension purposes.

    I think Selegiline needs to rank higher on this list for sure though! It has been shown to increase at least a couple different neural factors, very neuroprotective, and shown to increase the lifespan of multiple mammals. It is very difficult to test the effect of the drug on human lifespan but the science is absolutely there to show that it decreases brain again specifically concerning the catecholaminergic system which is essentially the brain's engine.

    Check Dr. Joseph Knoll out. He created this drug (Deprenyl/Selegiline). I have high hopes that I will be able to live a more bountiful life due to a few bad dopamine related genes. Most significant of mine is taq1a homozygous which encodes for 30-40% less dopamine d2 receptors. Studies demonstrate after age 45 years old, every decade equates to about a 13% decrease in dopamine. Once you exceed 70% striatal dopamine loss symptoms of Parkinson's disease physically show. I already have 30-40% less dopamine d2 receptors in the striatum. If I experience normal aging and loss of dopaminergic activity I am on my way to develop parkinsons symptoms by my late 60s to late 70s. Not with Selegiline.

  • Anthony C

    October 27, 2019 at 9:17 pm Reply

    why is Fasoracetam not higher up, to me it's very potent at low doses and also stronger and more pleasant than aniracetam . Also, what about Pramiracetam? does it have an overall pleasant feeling taking it. If someone could compare the two which is most pleasant Faso or praminracetam??
    Which one is more pleasant cbd oil or Tianeptine? Which is better for pleasant effects for relaxing effect? Is Tianeptine really so good?? THX

  • Johnny B Zen

    August 29, 2020 at 2:56 pm Reply

    University of Toronto? I didn't realize you're Canadian…or i forgot. LOL. Me too. Hey, i'm about to place an order with Nootropicsdepot.com and wanted to ask if there's a Canadian place to shop that would be better as a home base online store for me. Thanks for all the great content btw. I've learned so much from you. Keep it up !

  • Sober Serotonin

    September 11, 2020 at 9:12 pm Reply

    Be very careful about yohimbine dosage. nobody with high blood pressure or heart disease should take it. It’s a good idea to have propranolol on hand in case the potent sympathetic nervous system stimulation begins to bother you

  • Alma Quejada

    December 29, 2020 at 11:55 pm Reply

    Ok so we aren't going to talk about the flatmate doing the dishes noisily or playing drums with dishes and glasses? Lmao I have watched 3 videos and in ALL OF THEM there are those background noises

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