The Science Behind Pain | Can Supplements Really Help?
#pain #supplements #nootropicsdepot
Pain is a universal human experience, but understanding it can be quite complex. What are the different kinds of pain that we sense, and how does our mental state affect how we perceive pain? Learn about pain pathways, pain as a protective mechanism, and supplements that can help us manage pain acutely and long-term. The better we understand where pain comes from, the more equipped we are to manage pain and understand how our bodies sense the world around us. This month on the In Search of Insight Podcast, your hosts Emiel and Erika dive into an exciting conversation and discuss:
-Pain Pathways and Triggers
-Nociceptive Signals and Inflammatory Soup
-How Our Mental State Influences our Perception of Pain
-Pain as a Protective Mechanism
-Supplements that can Help Manage Pain
Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.
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Supplements for Pain Management
Longvida Curcumin
Rephyll
Kava
DL Phenylalanine
New Product Releases
ClariMag
Super B12
Chapters
0:00 Introduction
1:50 New Product Releases
2:00 Quick Dissolve Super B12
9:11 ClariMag
20:32 The Science Behind Pain
22:37 Nociception
27:32 TRPV1 Receptors – Temperature-Based Pain
33:12 The Inflammatory Soup
36:02 Mechanoreceptors – Mechanical-Based Pain
41:24 Nerve Growth Factor
47:43 Topical Products for Pain
59:20 Mechanical Pain & Perception
1:07:57 Menthol & Cold Sensitivity
1:13:34 TRPA1 Receptors
1:19:33 Alternative Methods for Pain Management
1:22:21 Supplements for Pain Management
1:22:58 Curcumin for Pain Management
1:29:00 Agmatine for Pain Management
1:30:22 Calcium for Pain Management
1:31:03 Kava for Pain Management
1:33:11 Does GABA Reduce Pain?
1:34:51 ClariMag for Pain Management
1:37:24 Pain as a Subjective Experience
1:39:51 Cannabinoid Receptors
1:41:11 Beta Carryophyllene for Pain Management
1:42:03 Palmitoylethanolamide for Pain Management
1:42:55 DL Phenylalanine for Pain Management
1:44:01 Acetyl L-Carnitine for Pain Management
1:44:43 Super B12 for Pain Management
1:47:20 Take a Multi-Faceted Approach with Pain
1:48:19 Conclusion
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6 Comments
Brandon Williams
Neat
Brandon Williams
I will be indestructible now
Dad
What do u guys think about Pumpkin Seed extract, P5P, and pyridoxal?
Chris Bent
Great podcast, as usual!
One question regarding agmatine –
I believe I've read in a study that in regards to adrenergic signaling – it depends on the dose if it is inhibited or increased? It may have been in regards to gastric adrenergic receptors specifically, IIRC…
Can you confirm that?
Would that mean that too much agmatine, like in the gram-doses that many people take- it may actually enhance perception of pain, while lower doses inhibit it?
InTrancedState
Hey you guys! Great podcast. Considering how prevalent heart disease is in the US, will you be doing a cardiovascular based podcast at some point? I know I'm worried about long term heart health and would like to know about supps that work directly on the heart as cardiotonics and indirectly on the vascular system. Would be an incredibly relevant podcast and you guys have a wide array of heart healthy supplements to go over
chickenturkey1
Can you guys talk about fenugreek on a future episode please? Thanks!